Indian Journal Watch: 8 November 2026

Indian Journal Watch, InfectionIndia.com

Indian Journal Watch

8 November 2026

Microbiology, infectious disease, AMR and infection-control papers from India and South Asia added to PubMed on 6 November 2026 and not covered in earlier issues (PubMed showed no new entries dated 7 to 8 November at the time of compilation).

Lead articles

Malaria · Surveillance gaps · American Journal of Tropical Medicine and Hygiene

Underappreciated Transmission of Plasmodium malariae and Plasmodium ovale: A Potential Barrier to Malaria Elimination in Bangladesh

American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.26-0557 · PubMed 42993973

What
An investigation by icddr,b of malaria cases escaping routine surveillance in Bandarban, Bangladesh, where field diagnosis relies on Plasmodium falciparum/P. vivax-specific rapid diagnostic tests (RDTs) and microscopy, and where P. malariae and P. ovale spp. remain absent from routine surveillance.
Design
Blood samples collected in 2025 from febrile patients who tested negative for P. falciparum/P. vivax by RDT underwent microscopy and SYBR-Green real-time qPCR targeting the 18S rRNA gene. P. ovale-positive cases were confirmed by probe-based qPCR, with P. ovale curtisi and P. ovale wallikeri identified using an assay targeting small subunit rRNA and Po-ldh genes. Archived laboratory records (2014-2024) were reviewed for previously detected P. malariae infections.
Key findings
In 2025, five P. ovale spp. (four P. ovale curtisi and one P. ovale wallikeri) and three P. malariae cases were detected in Alikadam Subdistrict. All were RDT-negative despite microscopically detectable parasitaemia (mean 4,536 parasites/µL for P. ovale and 6,053 parasites/µL for P. malariae). Field microscopy correctly diagnosed only one P. ovale case; the remaining four were misclassified as P. vivax or mixed P. malariae/P. vivax. Archived data revealed 25 additional qPCR-confirmed P. malariae infections, predominantly among adult males in forest-adjacent settlements.
Limitations
Case numbers are small and drawn from one district; only RDT-negative febrile patients were tested, and the abstract does not report the total number screened.
Relevance to South Asia
Bangladesh is approaching malaria elimination; the authors call for pan-species molecular diagnostics and species-specific case reporting in routine surveillance, an issue shared with other Pf/Pv RDT-dependent programmes in the region.

Vaccination · Urban slums · Global Health Research and Policy

Interventions to improve vaccination coverage among children aged 12-23 months in urban slum areas of Asia: A systematic review and meta-analysis

Global Health Research and Policy · doi:10.1016/j.ghrp.2026.08.002 · PubMed 42990976

What
A systematic review and meta-analysis of interventions to improve vaccination coverage among children aged 12-23 months in urban slum areas of Asia.
Design
Embase, PubMed and Cochrane were searched for articles published between 2010 and January 2026. Two investigators independently extracted data; bias was assessed with ROBINS-I and RoB 2, and certainty of evidence with GRADE. Effects were pooled as odds ratios (ORs) with 95% confidence intervals (CIs).
Key findings
Nine studies, from quasi-experimental designs to randomised controlled trials (RCTs), were conducted in Bangladesh, India, Indonesia and Pakistan, involving 37,405 children. Full vaccination coverage probably improved in only one RCT (OR 6.42, 95% CI 4.63-8.90) and in three quasi-experimental studies (OR 9.68, 95% CI 3.91-23.95) with high heterogeneity. DPT3 coverage significantly improved in two RCTs (OR 2.68, 95% CI 2.17-3.31; 1872 participants; I² = 0%), whereas quasi-experimental studies showed uncertain effects (OR 3.58, 95% CI 2.99-4.28; 31,817 participants; I² = 78%). Single or multicomponent strategies significantly increased coverage compared with controls.
Limitations
Included studies showed a moderate to high or serious level of bias; certainty of evidence was moderate in RCTs and very low in quasi-experimental studies, and intervention sustainability was limited.
Relevance to South Asia
Three of the four study countries are in South Asia; the authors call for further studies to improve coverage in this age group in Asian slums.

More from the journals

Vector-borne & parasitic diseases

Virology & vaccines

AMR & antimicrobial discovery

IPC, HAI & clinical infection

TB, mycology & diagnostics

Items are summaries of published abstracts and are not clinical advice. Readers should consult the original article. Figures are quoted as reported in each abstract.

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